Scientific Papers Published by TMDA Staff

Medicines and Complimentary Products Scientific Publications
1Mwamwitwa. K.W.,et al, "Quality Surveillance of Anti-Tuberculosis Medicines in Tanzania, 2012-2018, Journal of Medical Research and Health Education, 2021, Vol. 5 No. 2"
2Hiiti B. Sillo, Sunday Kisoma, Monika Zweygarth, Eliangiringa Kaale, Veronika Mugoyela, Lembit Rago: Medicines Regulation: Comparison of Medicines Legislation in the East African Community, WHO Drug Information Vol. 30, No. 4, 2016 http://www.who.int/medicines/publications/druginformation/WHO-DI_30-4_MedsRegulation.pdf
3Alambo K. Mssusa, Adam M. Fimbo, Alex F. Nkayamba, Henry F. Irunde, Hiiti B. Sillo, Danstan H. Shewiyo, Geraldine Hill, et al: Safety Profile of Artemether-Lumefantrine: A Cohort Event Monitoring Study in Public Health Facilities in Tanzania. Clinical Drug Investigation; ©Springer International Publishing Switzerland 2016 http://europepmc.org/abstract/med/26951203
4Rutta E, Liana J, Embrey M, Johnson K, Kimatta S, Valimba R, Lieber R, Shekalaghe E, Sillo H: Accrediting retail drug shops to strengthen Tanzania's public health system: an ADDO case study: J Pharm Policy Pract. J Pharm Policy Pract. 2015 Nov 19;8:29. doi: 10.1186/s40545-015-0049-z. eCollection 2015 https://www.ncbi.nlm.nih.gov/pubmed/26413304
5Lembit Rago*, Hiiti Sillo, Ellen ët Hoen, Monika Zweygarth Regulatory framework for access to safe, effective quality medicines: Antiviral Therapy 2014; 19 Suppl 3:69ñ77 (doi: 10.3851/IMP2902).
6Ellen F. M. ët Hoen,*, Hans V. Hogerzeil, Jonathan D. Quick, Hiiti B. Sillo: A quiet revolution in global public health: The World Health Organizationís Prequalification of Medicines Programme; © 2014 Macmillan Publishers Ltd. 0197-5897 Journal of Public Health Policy, 1ñ25 www.palgrave-journals.com/jphp.
7Adelard B. Mtenga, Neema Kassim, Won-Bo Shim, and Duck-Hwa Chung (2012). Efficiency of fractionated γ-irradiation to eliminate spores and vegetative forms of bacillus cereus from raw rice. Journal of Food Science and Biotechnology(In Press) https://link.springer.com/article/10.1007/s10068-013-0117-6
8Adelard B. Mtenga, Neema Kassim, Won-Gyeol Lee, Won-Bo Shim, Yohan Yoon and Duck-Hwa Chung (2012). Resistance of Bacillus cereus and its enterotoxin genes in ready-to-eat foods to γ-irradiation. Journal of Food Science and Biotechnology.
9N. Kassim, A. B. Mtenga, W. B. Shim, and D. H. Chung (2012). The in vitro and in vivo efficacy of hen IgY against Vibrio parahaemolyticus and Vibrio vulnificus. Journal of Microbiology and Biotechnology, (In Press). http://www.jmb.or.kr/journal/download.php?Filedir=../submission/Journal/022/&num=5066
10Won-Bo Shim, Gil-SooJe, Kyeongyeol Kim, Adelard B. Mtenga, Won-Gyeong Lee, Jeong-Un Song, Duck-Hwa Chung, Yohan Yoon 2012. Effect of irradiation on kinetic behavior of Salmonella Typhimurium and Staphylococcus aureus in lettuce and damage of bacterial cell envelope. Radiation Physics and Chemistry 81, (5), 566–571.
11Won-Bo Shim, Gil-SooJe, Kyeongyeol Kim, Adelard B. Mtenga, Won-Gyeong Lee, Jeong-Un Song, Duck-Hwa Chung, Yohan Yoon 2012. Effect of irradiation on kinetic behavior of Salmonella Typhimurium and Staphylococcus aureus in lettuce and damage of bacterial cell envelope. Radiation Physics and Chemistry 81, (5), 566–571
12Kindoli S., Lee HA, Kim JH. (2012) Properties of Bac W42, a bacteriocin produced by Bacillus subtilis W42 isolated from Cheonggukjang.Joural of Microbiology and biotechnology 22(8):1092-100. 2012
13Kindoli S., Heo K., Lee H, Kim JH (2012) Properties of an antimicrobial substance from Bacillus subtilis H27 isolated from Cheonggukjang."Journal of food science and biotechnology (in Press).
14Shewiyo, D.H.; Kaale, E.; Risha, P. G.; Dejaegher, B.; Smeyers-Verbeke, J.; Vander Heyden, Y.; HPTLC methods to assay active ingredients in pharmaceutical formulations: A Review of the method development and validation steps, J. Pharm. Biomed. Anal. 66 (2012) 11-23. www.ncbi.nlm.nih.gov/pubmed/22494517
15D. H. Shewiyo, E. Kaale, P. G. Risha, B. Dejaegher, J. Smeyers – Verbeke, Y. Vander Heyden, Optimization of a RP-HPTLC method for the separation of isoniazid, ethambutol, rifampicin and pyrazinamide in fixed-dose combination antituberculosis tablets, Accepted for publication in J. Chromatogr. A, 2012, doi:org/10.1016/).chroma.2012.08.044 www.ncbi.nlm.nih.gov/pubmed/22981506
16Minzi O., Ngaimisi E., Shewiyo DH., Sasi P., Ignas AM., Interlaboratory development and cross validation of a chromatographic method for determination of lumefantrine in human plasma- A proficient capacity assessment of bioanalytical laboratories in Easy Africa, J. Anal. Bioanal. Techniques, 3 (2012) doi.org/10.4172/2155-9872.1000131 www.omicsonline.org/interlaboratory-development-and-cross-validation-of-a-chromatographic-method-for-determination-of-lumefantrine-in-human-plasma-a-proficient-capacity-assessment-2155-9872.1000131.php?aid=654
17Edmund Rutta, Bryceson Kibassa, Brittany McKinnon, Jafary Liana, Romuald Mbwasi, Wilson Mlaki, Martha Embrey, Michael Gabra, Elizabeth Shekalaghe, Suleiman Kimatta and Hiiti Sillo: Increasing Access to Subsidized Artemisinin- based Combination Therapy through Accredited Drug Dispensing Outlets in Tanzania: Health Research Policy and Systems 2011, 9:22 http://www.health-policy-systems.com/content/9/1/22. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141785/
18Neema Kassim, Adelard B. Mtenga, Won-Gyeong Lee, Jeong-Sook Kim, Won-Bo Shim, and Duck-Hwa Chung (2011). Production of Coturnix Quail Immunoglobulins Y (IgYs) against Vibrio parahaemolyticus and Vibrio vulnificus. Journal of Food Science and Biotechnology, 20(6); 1577-1583
19N. Kassim, K. Kim, A. B. Mtenga, J-E. Song, Q. Liu, W.-B. Shim, D-H. Chung (2011). A preliminary study of T-2 and HT-2 toxins in cereals sold in traditional market in South Korea. Journal of Food Control, 22; 1408-1412.
20Shewiyo, D.H.; Kaale, E.; Risha, P. G.; Ugullum, C.; Sigonda, M. N.; Dejaegher, B.; Smeyers-Verbeke, J.; Vander Heyden, Y.; Development and validation of a normal phase HPTLC method for simultaneous analysis of Lamivudine, Stavudine and Nevirapine in fixed dose combination tablets, Journal of Pharmaceutical and Biomedical Analysis 54 (2011) 445 – 450
21Shewiyo, D.H.; Kaale, E.; Risha, P. G.; Sillo, H. B.; Dejaegher, B.; Smeyers-Verbeke, J.; Vander Heyden, Y.; Development and validation of a normal-phase HPTLC-densitometric method for quantitative analysis of Fluconazole in tablets, Journal of Planar Chromatography 24 (2011) 529 – 533
22Adelard B. Mtenga, Neema Kassim, Won-Gyeong Lee, Rok-Won Heo, Won-Bo Shim, Yohan Yoon, and Duck-Hwa Chung (2011). Effect of Low Dose γ-Irradiation on the Fate and Cell Envelope of Bacillus cereus, Escherichia coli and Salmonella Typhimurium. Korean Journal of Food Science of Animal Resources, 31(6); 843~850.
23Mi Sook Cho, Kyeongyeol Kim, Eunkyoung Seo, Neema Kassim, Adelard Bartholomew Mtenga, Won-Bo Shim, Soo-Hyung Lee, and Duck-Hwa Chung (2010). Occurrence of Patulin in Various Fruit Juices from South Korea: An Exposure Assessment. Journal of Food Science and Biotechnology, 19(1); 1-5.
24Shewiyo, D.H.; Kaale, E.; Risha, P. G.; Dejaegher, B.; Smeyers-Verbeke, J.; Vander Heyden, Y.; Development and validation of a normal phase high-performance thin layer chromatographic method for the analysis of sulfamethoxazole and trimethoprim in co-trimoxazole tablets, Journal of Chromatography A 1216, (2009) 7102 – 7107
25Kayumba, P.C.; Risha, P.G.; Shewiyo, D.; Msami, A.; Masuki, G.; Ameye, D.; Vergote, G; Ntawukuliryayo, J. D.; Remon, J. P.; The quality of essential antimicrobial and antimalarial drugs marketed in Rwanda and Tanzania: influence of tropical storage conditions on in vitro dissolution. Journal of Clinical Pharmacy; Therapeutics Volume 29 Issue 4 Page 331 - August 2004.
26Minzi, O. M. S.; Moshi, M. J.; Hipolite, D.; Massele, A. Y.; Tomson G.; Ericsson, O.; Gustafson, L. L. Evaluation of the quality of amodiaquine and sulphadoxine/pyrimethamine tablets sold by private wholesale pharmacies in Dar es Salaam Tanzania. Journal of Clinical Pharmacy; Therapeutics Volume 28 Issue 2 Page 117 - April 2003.
27Risha, P.G.; Shewiyo, D.; Msami, A.; Masuki, G.; Vergote, G.; Vervaet, C.; Remon, J.P. In vitro evaluation of the quality of essential drugs on the Tanzanian market. Tropical Medicine & International Health Volume 7 Issue 8 Page 701 - August 2002
28Sophia Mziray, Kissa Mwamwitwa, Sunday Kisoma, Siya Augustine, Adam Fimbo, Danstan Hipolite, Hiiti Sillo and Eliangiringa Kaale :Post Marketing Surveillance of Anti-malarial Medicines in Tanzania :Pharm Regul Aff 6: 191. doi:10.4172/2167-7689.1000191 https://www.omicsonline.org/open-access/post-marketing-surveillance-of-antimalarial-medicines-in-tanzania-2167-7689-1000191.php?aid=90566
Laboratory Scientific Publications
1Mwalwisi, Yonah H., et al. "Development and validation of a high-performance thin-layer chromatography method for the determination of artesunate and amodiaquine in tablet formulations." JPC-Journal of Planar Chromatography-Modern TLC 30.4 (2017): 307-312. Development and validation of a high-performance thin-layer chromatography method for the determination of artesunate and amodiaquine in tablet formulationstd>
2Mwalwisi, Yonah H., et al. "Development of a Simple, Rapid, and Robust Isocratic Liquid Chromatographic Method for the Determination of Pyrimethamine and its Synthetic Impurities in Bulk Drugs and Pharmaceutical Formulations." Chromatographia 80.9 (2017): 1343-1352. Development of a Simple, Rapid, and Robust Isocratic Liquid Chromatographic Method for the Determination of Pyrimethamine and its Synthetic Impurities in Bulk Drugs and Pharmaceutical Formulations
3Mwalwisi, Yonah H., et al. "Development of a simple, rapid, and robust liquid chromatographic method for the simultaneous determination of sulfalene, sulfadoxine, and pyrimethamine in tablets." Journal of pharmaceutical and biomedical analysis 129 (2016): 558-570. Development of a simple, rapid, and robust liquid chromatographic method for the simultaneous determination of sulfalene, sulfadoxine, and pyrimethamine in tablets
4Höllein, L., Kaale, E., Mwalwisi, Y. H., Schulze, M. H., Holzgrabe, U. (2016). Routine quality control of medicines in developing countries: analytical challenges, regulatory infrastructures and the prevalence of counterfeit medicines in Tanzania. TrAC Trends in Analytical Chemistry, 76, 60-70. Routine quality control of medicines in developing countries: analytical challenges, regulatory infrastructures and the prevalence of counterfeit medicines in Tanzania
5Y., et al. "The chemical and pharmaceutical equivalence of sulphadoxine/pyrimethamine tablets sold on the Tanzanian market." Journal of clinical pharmacy and therapeutics 30.6 (2005): 575-581. The chemical and pharmaceutical equivalence of sulphadoxine/pyrimethamine tablets sold on the Tanzanian market Hebron,